General Cell Based Assays
Abcam Pyrophosphate Assay Kit (Colorimetric / Fluorometric)
Pyrophosphate Assay Kit (Colorimetric / Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Chloride Assay Kit suffici
Chloride is an essential anion needed for the proper functioning of many critical aspects of metabolism including aiding in maintenance of the body acid-base balance. In Cystic fibrosis mutations to the Cf transmembrane conductance regulator (CfTCR) gene result in altered sodium and chloride ion transport channels.
Cayman Chemical 33-BCRP InhIbItr 1mg
A BCRP inhibitor; sensitizes mitoxantrone-resistant H460/MX20 cells to mitoxantrone-induced cell death alone and in combination with UV radiation; sensitizes KB-C2 cells overexpressing P-gp to colchicine-induced cell death; increases intracellular accumulation of mitoxantrone in H460/MX20 cells at 5 µM
Eurofins Discoverx PathHunter eXpress PDGFRb Functional Assay, 10-Plate Kit. (93-0493E3CP16L)
The PathHunter eXpress PDGFRb Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated PDGFRb dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged PDGFRb and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCXCR4 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0481E3MCP5L)
The PathHunter mCXCR4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL12/SDF-1α) based activation of mCXCR4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCXCR4 and EA-tagged β-Arrestin-2. Activation of mCXCR4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rPROKR2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0482E2RCP0M)
The PathHunter rPROKR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokineticin) based activation of rPROKR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rPROKR2 and EA-tagged β-Arrestin-2. Activation of rPROKR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sigma Aldrich Fine Chemicals Biosciences Bilirubin Assay Kit suffic
Bilirubin also known as hematoidin is a degradation product formed as a result of heme catabolism in the liver. Bilirubin circulates in the blood stream as either the unconjugated insoluble form (indirect bilirubin) or the soluble glucuronide-conjugated form (direct bilirubin). Conjugated bilirubin moves from the bile canaliculi of the liver to the gall bladder where it is excreted into the small intestine during digestion. High levels of bilirubin can result in jaundice and may indicate liver disease blood disorders or blockage of the bile ducts.
Sigma Aldrich Fine Chemicals Biosciences Invertase Activity Assay K
Invertase (beta-fructofuranosidase) is an enzyme that catalyzes the hydrolysis of sucrose to fructose and glucose. Invertase is produced by certain plants microorganisms and honey bees.
Abcam TMRM Assay Kit (Mitochondrial Membrane Potential)
TMRM Assay Kit (Mitochondrial Membrane Potential)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress ADRB1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0488E2CP0L)
The PathHunter ADRB1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRB1 and EA-tagged β-Arrestin-2. Activation of ADRB1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ILS INFRARED LABORATORY SYSTEMS LLC Synermed UV340-R LDH
Liquid-Stable Ready-to-Use ReagentsExtended "On-Board" StabilityLinear to 1,000 U/L
Abcam NQO1 Activity Assay Kit
NQO1 Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement