General Cell Based Assays
Cayman Chemical Lipid Droplets Assay Oil Red
A Cdk4 inhibitor (Ki 0.6 nM for Cdk4/cyclin D1) selective for Cdk4 over Cdk6 (Ki 13.9 nM for Cdk6/cyclin D3) increases senescence in HR HER2- breast cancer cells in vitro but does not induce cell death in combination with fulvestrant
Cayman Chemical Acetaldehyde asy Reagent 200uL
A Clk1 Clk2 and Clk4 inhibitor (IC50s 8 20 and 12 nM respectively) selective for these kinases over Clk3 (IC50 >3000 nM) as well as DYRK1A DYRK1B DYRK2 HIPK1 and HIPK3 (IC50s 213 956 1309 187 and 159 nM respectively) but does inhibit HIPK2 (IC50 23 nM)
Cayman Chemical 2-bromo 17-EstradIol 5mg
A synthetic steroid and inhibitor of estrogen 2-hydroxylase; inhibits estrogen 2-hydroxylase in rat liver microsomes at 50 and 100 µM; prevents estrogen-induced inhibition of apomorphine-induced climbing behavior in mice at 5 mg/kg
Cayman Chemical UrIc AcId Enzyme MIxture 1ea
An H /K -ATPase inhibitor reversibly inhibits the activity of the H /K -ATPase in an enzyme assay inhibits histamine-induced gastric acid secretion in rats at 30 mg/kg s.c.
Cayman Chemical ML-148 asy Reagent 25uL
A C-glycoside flavonoid with diverse biological activities reduces H